Our Team

We are experienced clinicians and researchers—specialists in infectious disease, genomics and next-generation sequencing technologies—who are passionate about leveraging the power of technology to advance human health and quality of life.

Crystal R Icenhour, PhD
CEO and Co-Founder
Crystal R Icenhour, PhD
CEO and Co-Founder

Dr. Crystal R. Icenhour, Ph.D. is one of the rising stars of American biotechnology. As founding CEO of Aperiomics, she brings more than 25 years in medical research and leads the company’s mission to harness the power of next-generation DNA sequencing to identify every known pathogen – bacteria, virus, fungi or parasite – within a single test.

Throughout Dr. Icenhour’s career, she has been a leader in both business and science, bridging the translational gap between these two worlds through technology. A seasoned entrepreneur, she previously served as President and Chief Science Officer for Phthisis Diagnostics in Charlottesville, Virginia – a research and development company developing easy-to-use molecular diagnostics for intestinal parasites. Dr. Icenhour holds two patents, has authored and co-authored numerous research articles and theses, and has been a prolific speaker and presenter at scientific conferences. She has served on review panels for the National Science Foundation, the Environmental Protection Agency, and National Institutes of Health Small Business Innovation Research Program.

Dr. Icenhour serves as Chairman of Virginia BIO and was chosen to participate in the Springboard Enterprises 2016 class of women-led companies. She received her Ph.D. in Pathobiology and Molecular Medicine from the University of Cincinnati Medical School of Graduate Studies in 2002. Following the completion of her graduate degree, Dr. Icenhour conducted postdoctoral research at the Mayo Clinic College of Medicine and the Department of Infectious Diseases at Duke University Medical Center, where she currently serves as an adjunct assistant professor.

C. Alexander Valencia, PhD
Chief Clinical Officer
C. Alexander Valencia, PhD
Chief Clinical Officer

Dr. C. Alexander Valencia, Ph.D. is a skilled molecular geneticist and an expert in translating next-generation sequencing technology into clinical practice through the development and implementation of clinical assays, interpretation of genomic data and by associating novel genes to human diseases. As Aperiomics’ Chief Clinical Officer, he oversees clinical test development, validations, regulatory affairs and operations on behalf of the company.

With over a decade of administration experience in major laboratories across the United States, Dr. Valencia has managed teams of technologists, project managers, genetic counselors, marketing specialists, and bioinformaticians. Prior to joining Aperiomics, he served as the molecular laboratory director at Cincinnati Children’s Hospital Medical Center and PerkinElmer Genomics. Setting the standard for genetics in medical practice, Dr. Valencia has made significant contributions in the field of clinical genomics, publishing more than 50 peer-reviewed articles and speaking at numerous conferences.

Dr. Valencia received his Ph.D. from Carleton University and the University of Ottawa and completed his post-doctoral studies in biochemistry/molecular biology and clinical molecular genetics at the University of North Carolina Chapel Hill and Emory University, respectively.

Elizabeth P Pyle
Chief Operating Officer
Elizabeth P Pyle
Chief Operating Officer

Elizabeth P. Pyle is a seasoned executive with an extensive background in business development, strategic planning, marketing, and operations management. In her role as Aperiomics’ Chief Operating Officer, Ms. Pyle oversees corporate operations and quality assurance of Aperiomics’ DNA-testing services.

Prior to joining Aperiomics, Ms. Pyle directed the University of Virginia’s National Science Foundation Innovation-Corps Program, designing undergraduate and graduate curricula for the School of Engineering & Applied Sciences’ Technology Entrepreneurship Program. She also founded Pyle & Associates, LLC – an Interim Executive Management firm providing customized consulting for clients operating across several diversified industries.

Ms. Pyle holds a M.B.A. degree from Averett University, a M.Ed. from the University of Houston, and a B.A. in Geology from Cedar Crest College. She has served on various boards including the Board of Directors for the Charlottesville Venture Group, where she chaired the Business Plan Review and Annual Business Forum Committees.


Board of Directors

Dr. Keith Crandall, PhD
Co-Founder
Dr. Keith Crandall, PhD
Co-Founder
Crystal R Icenhour, PhD
CEO and Co-Founder
Crystal R Icenhour, PhD
CEO and Co-Founder

Dr. Crystal R. Icenhour, Ph.D. is one of the rising stars of American biotechnology. As founding CEO of Aperiomics, she brings more than 25 years in medical research and leads the company’s mission to harness the power of next-generation DNA sequencing to identify every known pathogen – bacteria, virus, fungi or parasite – within a single test.

Throughout Dr. Icenhour’s career, she has been a leader in both business and science, bridging the translational gap between these two worlds through technology. A seasoned entrepreneur, she previously served as President and Chief Science Officer for Phthisis Diagnostics in Charlottesville, Virginia – a research and development company developing easy-to-use molecular diagnostics for intestinal parasites. Dr. Icenhour holds two patents, has authored and co-authored numerous research articles and theses, and has been a prolific speaker and presenter at scientific conferences. She has served on review panels for the National Science Foundation, the Environmental Protection Agency, and National Institutes of Health Small Business Innovation Research Program.

Dr. Icenhour serves as Chairman of Virginia BIO and was chosen to participate in the Springboard Enterprises 2016 class of women-led companies. She received her Ph.D. in Pathobiology and Molecular Medicine from the University of Cincinnati Medical School of Graduate Studies in 2002. Following the completion of her graduate degree, Dr. Icenhour conducted postdoctoral research at the Mayo Clinic College of Medicine and the Department of Infectious Diseases at Duke University Medical Center, where she currently serves as an adjunct assistant professor.

George Lula
Director
George Lula
Director
Stacy Baines Manvitz
Director
Stacy Baines Manvitz
Director
Rene Lewin
Director
Rene Lewin
Director

Science Advisory Board

Dr. Evan Johnson, PhD, Chairman
Chairman, Co-Founder
Dr. Evan Johnson, PhD, Chairman
Chairman, Co-Founder
Dr. Keith Crandall, PhD
Co-Founder
Dr. Keith Crandall, PhD
Co-Founder

Founders

Dr. Keith Crandall, PhD
Co-Founder
Dr. Keith Crandall, PhD
Co-Founder
Crystal R Icenhour, PhD
CEO and Co-Founder
Crystal R Icenhour, PhD
CEO and Co-Founder

Dr. Crystal R. Icenhour, Ph.D. is one of the rising stars of American biotechnology. As founding CEO of Aperiomics, she brings more than 25 years in medical research and leads the company’s mission to harness the power of next-generation DNA sequencing to identify every known pathogen – bacteria, virus, fungi or parasite – within a single test.

Throughout Dr. Icenhour’s career, she has been a leader in both business and science, bridging the translational gap between these two worlds through technology. A seasoned entrepreneur, she previously served as President and Chief Science Officer for Phthisis Diagnostics in Charlottesville, Virginia – a research and development company developing easy-to-use molecular diagnostics for intestinal parasites. Dr. Icenhour holds two patents, has authored and co-authored numerous research articles and theses, and has been a prolific speaker and presenter at scientific conferences. She has served on review panels for the National Science Foundation, the Environmental Protection Agency, and National Institutes of Health Small Business Innovation Research Program.

Dr. Icenhour serves as Chairman of Virginia BIO and was chosen to participate in the Springboard Enterprises 2016 class of women-led companies. She received her Ph.D. in Pathobiology and Molecular Medicine from the University of Cincinnati Medical School of Graduate Studies in 2002. Following the completion of her graduate degree, Dr. Icenhour conducted postdoctoral research at the Mayo Clinic College of Medicine and the Department of Infectious Diseases at Duke University Medical Center, where she currently serves as an adjunct assistant professor.

Dr. Evan Johnson, PhD, Chairman
Chairman, Co-Founder
Dr. Evan Johnson, PhD, Chairman
Chairman, Co-Founder
Eduardo Castro-Nallar
Co-Founder
Eduardo Castro-Nallar
Co-Founder